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Salvianolic acids even have a good impact while in the treatment method of lung cancer and liver cancer. Li et al. (2002) identified that Sal A inhibited the growth of mouse lung most cancers cells by inhibiting the expression of c-myc and P46 (JNK/SAPK). In vivoCells have evolved two major pathways for apoptosis; extrinsic or death receptor pathwa

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133). Therefore, focusing on PYCR has been attempted134,one hundred thirty five with confined preclinical efficacy info. A suicide inhibitor for PRODH has actually been identified136 and found for being synthetically lethal While using the p53-activated point out and together with glutaminase inhibition. These inhibitors await further more developm

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